Leukemia and lymphoma:
- Date
- February 17, 2017
We observed that a subgroup of patients with myelodysplastic syndrome (MDS) carrying a gene variant of the transcriptional repressor GFI1 (GFI136N) is more resistant to treatment […]- Date
- February 18, 2017
Lymphoma and leukemia are both cancers of blood cells, blood cell precursors or even blood stem cells that are programmed to form blood cells. While a […]
Transcriptional control of hematopoiesis
- Date
- March 7, 2017
In leukemia, a form of blood cancer, cells from the bone marrow multiply without control and invade the bloodstream and other organs. This compromises the function […]- Date
- March 7, 2017
When cells are subjected to gamma irradiation or certain chemotherapeutic drugs, the chromosomes and in particular the DNA within the chromosomes are damaged. As a consequence, […]- Date
- March 7, 2017
Gfi1 is participating in the early steps of pro-T cell and a number of target genes have been identified for Gfi1 such as Id1, 2, both […]
Rare blood cell disorders
- Date
- March 7, 2017
Platelets are essential for blood clotting and are formed in the bone marrow by large cells, so-called “megakaryocytes”, which form long protrusions that penetrate into blood […]
